The aim of the Journal is to advance the development of a hierarchical and functional integrative approach to the neurosciences with an emphasis on: (i) neuroimaging, (ii) comparative experimentation, and (iii) data driven modeling, including the theoretical and philosophical foundations of this approach.The scope of the Journal is broad, encompassing all aspects of brain function, including regulation of homeostatic and maintenance functions, and behaviors in health and disease.The Journal will promote and disseminate studies categorized under the following themes: * Theoretical methods and analytical techniques allowing integration in neuroscience (e.g., infinite dimensional nonlinear dynamical systems, theory of complexity, n-field theory, diffusion theory, category theory, graph theory); * Experimentally and mathematically integrated models of brain activity (e.g., volume transmission and deep brain stimulation, large-scale realistic cable networks of cortical and sub-cortical integration); * Functional integration of physiological control mechanisms with anatomical structure in the nervous system, central and peripheral (e.g., control and regulation in the cardio-vascular and respiratory systems, autonomic control); * Bio-engineering and experimental techniques allowing integration in neuroscience (e.g., Human-machine interface technology, brain-based devices, optical recording, multi-electrode arrays, neuroimaging); * Experimentally-based neuropsychological and neurophilosophical models (e.g., semantic ambiguity, anticipatory behavior, free will, epistemological limitations in understanding consciousness); * Applications of integration to neural pathologies and neural control physiology (e.g., brain diseases, plasticity and rehabilitation, interface between functional genomics and psychiatric illnesses).The following types of experimental and theoretical papers are suitable for the Journal: * Rapid communications and forum style commentary articles (approx. 16 pages; 20 citations) * Original articles containing research reports (approx. 40 pages; 60 citations) * Topical reviews containing critical survey of the literature (approx. 40 pages; 120 citations) * Book reviews.